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Molecular Cardiac Physiology Group

Alia Arslanova, PhD Candidate

Supervisor: Dr. Glen Tibbits

Email: arslanov@sfu.ca

"My research focuses on investigating the mechanisms of the cardiac arrhythmia condition known as catecholaminergic polymorphic ventricular tachycardia (CPVT) using human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). This study utilizes a variety of techniques including CRISPR-Cas9 genome editing, multielectrode arrays assay, optical mapping and patch clamping, and has a potential to contribute to disease modelling and personalized medicine in vitro using a hiPSC-CM model."

Josh Ham, PhD Student

Supervisor: Dr. Damon Poburko

Email: josh_ham@sfu.ca

"My research focuses on investigating the mechanisms of the cardiac arrhythmia condition known as catecholaminergic polymorphic ventricular tachycardia (CPVT) using human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). This study utilizes a variety of techniques including CRISPR-Cas9 genome editing, multielectrode arrays assay, optical mapping and patch clamping, and has a potential to contribute to disease modelling and personalized medicine in vitro using a hiPSC-CM model."

Diana Hunter, Postdoctoral Fellow

Supervisor: Dr. Thomas Claydon

Email: dhunter@sfu.ca

"As a Michael Smith Health Research BC funded Postdoctoral Fellow in the Claydon Lab, I am using the powerful technique of CRISPR gene editing in induced pluripotent stem cells to create models to study the (dys)function of potassium channels in both cardiomyocytes (heart) and neuronal (brain) cells."

Harshinia Nadig Seetharam, PhD Student

Supervisor: Dr. Thomas Claydon

Email: hns@sfu.ca

"I have always been keen on the biophysical aspects of life. With a strong background in Biochemistry and structural biology, at Dr. Claydon lab I am trying to understand electrophysiology of cardiomyocytes at molecular levels."